Our PPR based DNA/RNA editing technology will bring innovation in a wide range of fields, including medical, chemical, and agriculture.


RNA targeting / editing

Mode of action
PartnerScreeningCell POCAnimal POCNon-clinical
EF-305Eye (AMD)/
RNA regulation
Japan Innovative Therapeutics, Inc.
RNA regulation
RNA regulation
Abbreviations: CNS: Central nerve system; AMD: Age-related macular disease; POC: Proof of concept


We focus mainly on target molecules / functions with special characteristics of PPR, and disease areas with highest market needs.

RNA targeting /editing
  • Splicing

    Advanced and precise control than nucleic acid medicine

  • RNA with
    unknown function

    Repeat RNA, lncRNA etc.

  • Cell therapy

    Activation of Genomic editing in ex vivo uses

Disease area
  • Easily accessible diseased area

    Drug delivery system has already been established, such as ophthalmological field

  • Neurodegenerative disease

    Neurological disorder, caused by RNA
    It is not effective with nucleic acid medicine

  • Cancer · immunity

    Activation of allogeneic CAR-T

  • Others

    Rare disease(s)

Potential Segments

Global warming, depletion of resources, and destruction of ecosystems are becoming more serious due to the rapid increase in the world’s population, and the global environment, which is the foundation for the continued existence of mankind, is reaching its limit. We aim to create a sustainable society in which people and a variety of animals and plants can coexist and maintain the productivity of nature.


Many vaccines, chemical compounds, bioethanol, and plastics are manufactured using biological systems such as microbes and plants. PPR proteins can optimize biomanufacturing by modifying genetic sequences (DNA manipulation) as well as their expression circuit (DNA/RNA manipulation). EditForce’s innovative DNA/RNA manipulation technology offers solutions to effective biomanufacturing.

Target areas

・Chemical products


Food and agricultural sustainability are one of the critical global challenges we face today. Genome editing, capable of more accurate and rapid plant modifi¬cation than conventional genetic recombination technology, will be key in achieving cost-effective and constantly high crop yields to solve these problems.

Target areas

・Yield improvement
・Environmental resistance